For rectal administration, contents of the vials should be diluted as follows:
FOR RECTAL ADMINISTRATION
Administration—Dosage is highly individualized; the drug should be administered only by those completely familiar with its quantitative differences from other barbiturate anesthetics.
Pediatric Patients Older Than 1 Month of Age—Brevital® Sodium is administered rectally as a 1% solution.
Induction of Anesthesia—For rectal administration, the usual dose for induction is 25 mg/kg using the 1% solution.
WARNING
Brevital should be used only in hospital or ambulatory care settings that provide for continuous monitoring of respiratory (e.g. pulse oximetry) and cardiac function. Immediate availability of resuscitative drugs and age- and size-appropriate equipment for bag/valve/mask ventilation and intubation and personnel trained in their use and skilled in airway management should be assured. For deeply sedated patients, a designated individual other than the practitioner performing the procedure should be present to continuously monitor the patient. (See WARNINGS)
